Damiano Barone, M.D.

Damiano Barone earned his M.D. from the University of Naples Federico II, then completed a neurosurgery residency at Cambridge University Hospitals. During his training, he took time out to pursue a Ph.D. in Clinical Neurosciences at the University of Cambridge, focusing on foreign body responses to neural implants and strategies for promoting tissue repair. He followed this with a postdoctoral fellowship in electrical engineering, refining thin-film device manufacturing and computational modeling to improve neural interface design. Subsequently, he undertook specialized fellowships in functional and peripheral nerve neurosurgery at the Walton Centre and the Mayo Clinic, enabling him to integrate advanced technological innovations into patient-centric surgical care. His lab focuses on designing seamless neural interfaces that mimic tissue mechanics while delivering precise recording and stimulation. A key goal is to create minimally invasive implants that expand in place, conform to delicate neural structures, and provide high-density neural mapping with minimal disruption. This group also pioneers “biohybrid” implants, combining cells or biologically active coatings with flexible electronics to enhance the long-term integration of devices into the host nervous system. By studying how neural tissues respond at the molecular level, they develop coatings and scaffold architectures that diminish scarring, extend device functionality, and ensure that implanted electrodes can faithfully capture and modulate signals over the course of therapy.

Rice Neuroengineering Initiative

neuro@rice.edu

Mailing Address

Rice Neuroengineering Initiative | 6500 Main St. | Suite 906 | Houston, TX 77030